In this work, we employed generalized additive modeling to describe changes albumin and alpha-1-acid glycoprotein concentrations in pregnant and postpartum individuals living with HIV. _Front Pediatr. 2021 Oct 13;9:721059_
We report the results of a model-based analysis indicating hydroxychloroquine lung concentrations may be too low to exert an antiviral effect for treatment of COVID-19 in children and adults. _JAMA Pediatr. 2020;174(10):e202422_
In this study, we evaluated the pharmacokinetics of the atypical antipsychotic olanzapine in children, from infants to adolescents. Based on our analysis, we developed preliminary dosing recommendations for children. _Br J Clin Pharmacol. 2020 Jun 4_
We examined the pharmacokinetics of the opioid analgesic fentanyl in a cohort of 32 children, the majority of whom were obese. We utilized a novel probability-based strategy to optimize dosing of continuous fentanyl infusions in obese children. _J Clin Pharmacol. 2019 Dec 8;10.1002/jcph.1562_